| From targeted drug delivery
to biologically inspired materials design, Biomaterials
and Tissue Engineering research combines engineering
techniques with biology, chemistry and physics. Molecular
to cellular to tissue level research allows for an udnerstanding
of the underlying biological mechanisms which leads to
biomimetic materials development.
Recent Research Activities
| • |
Biocompatibility and Hemocompatibility |
| • |
Biomimetic Materials |
| • |
Controlled Release Drug Delivery |
| • |
Cardiovascular Biomaterials |
| • |
Cardiovascular Tissue Engineering |
| • |
Polymeric surface coatings for implants and sensors |
| • |
Hard & Soft Tissue Biomechanics |
| • |
Host-Biomaterial Interactions |
| • |
Nanoscale Orthopedic Biomaterials |
| • |
Targeted Drug/Gene Delivery |
Biomaterials & Tissue Engineering Faculty
|
Primary Faculty
|
Research Interests
|
Email Address
|
ALSBERG,
Eben |
Biomimetic tissue engineering;
innovative biomaterials and drug delivery vehicles
for functional tissue regeneration and cancer therapy;
control of stem cell differentiation; mechanotransduction
and the influence of mechanics on cell and tissue
function. |
ea@case.edu |
BASKARAN,
Harihara |
Microvascular tissue
engineering, cell migration in wound healing, inflammation,
and cancer metastasis |
hxb35@case.edu |
EPPELL,
Steven |
Nanoscale instrumentation
for biomaterials; bone and cartilage |
sje@case.edu |
KNOTHE
TATE,
Melissa |
Development of preventative, treatment and replacement measures for bone
disease and failure; Multi-scale modeling of the interplay between
mechanics and transport in biological systems: cell mechanics => tissue
engineering |
knothetate@case.edu |
MARCHANT,
Roger E. |
Surface modification
of cardiovascular devices; molecular level structure
and function of plasma proteins; liposome drug delivery
systems; mechanisms of bacterial adhesion to biomaterials |
rxm4@case.edu |
SEN GUPTA,
Anirban |
Development and surface-modification of lipidic and polymeric nanoparticles for "targeting" cardiovascular and cancer pathology, thereby providing a platform for "targeted nanomedicine and molecular imaging"; development and characterization of novel amino-acid based polymeric systems for potential application in tissue engineering scaffolds. |
anirban.sengupta@case.edu |
VON
RECUM,
Horst |
Tissue engineered epithelia;
pre-vascularized polymer scaffolds for tissue engineering;
directed stem cell differentiation; novel stimuli
responsive biomaterials for gene and drug delivery;
systems biology approaches to the identification
of angiogenic factors. |
hav1@case.edu |
| |
|
Associated Faculty
|
Research Interests
|
Email Address
|
ANDERSON,
James M. |
Biocompatibility of implants |
jma6@case.edu |
DOERSCHUK,
Claire |
Regulation of the inflammatory
response in the lungs, particularly the recruitment
of white blood cells, during pneumonia, sepsis, and
the acute respiratory distress syndrome |
cmd22@case.edu |
GRAHAM,
Linda M. |
Carotid artery surgery,
venous disease, abdominal aortic aneurysm repair,
peripheral artery/vein repair/bypass surgery, research
of vascular grafts |
lxg6@case.edu |
JOHNSTONE,
Brian |
Chondrogenesis, cartilage
regeneration, mesenchymal stem cells, tissue engineering
and mechanobiology |
bxj9@case.edu |
KOTTKE-MARCHANT,
Kandice |
Interaction of blood
and materials |
marchantk@po.lab.ccf.org |
RIMNAC,
Clare |
Mechanical performance
of orthopaedic total joint replacements through
fundamental materials studies and implant retrieval
analysis; skeletal fragility of bone tissue
(damage accumulation and repair); design and
manufacture of resorbable polymeric scaffolds
for bone tissue regeneration and repair. |
Clare.Rimnac@case.edu |
ZBOROWSKI,
Maciej |
Magnetic separation of
cells |
zborow@bme.ri.ccf.org |
ZIADY
Assem G. |
Self assembling non-viral gene therapy vectors; Proteomics in cystic fibrosis; Redox mediated inflammatory signaling in the lung. |
agz2@case.edu |
ZIATS
Nicholas P. |
Vascular grafts; vascular
cells; blood vessels |
npz@case.edu |
Affiliated Labs and Centers
|
