Guanshu Liu (L) and Yuguo Li (R) |
Guanshu Liu and Yuguo Li were recently honored for presenting a "Top Ten" research study that was advertised at the Joint Meeting of the Society for Molecular Imaging and Academy of Molecular Imaging, Sep 8-11, 2007. This honor was given to the ten highest-scored abstracts of approximately 1000 presentations. Their presentation, entitiled "A New Class of PARACEST MRI Contrast Agents for in vivo pH Measurements", described the development and application of a non-invasive method for monitoring pH, which is an important measurement for diagnosing metastatic cancers and other pathologies. An advantage to their approach involves a new type of chemical agent that can measure pH without also needing to measure the concentration of the agent in the pathological tissue. According to Prof. Marty Pagel, who collaborated with Guanshu and Yuguo to develop this MRI method, "the ability to measure tissue pH with a single MRI scan has great potential for translation to the clinic. The combination of the synthetic chemistry, radiology, and engineering analyses required for this project is a testament to Guanshu's and Yuguo's strong interedisciplinary talents as biomedical engineers." Guanshu, Yuguo, and Marty performed these studies within the Contrast Agent Molecular Engineering Laboratory (CAMEL) and the Case Center for Imaging Research (CCIR), which provides an unparalleled research environment for molecular imaging.
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