BIOMEDICAL ENGINEERING

Dr. Xin Yu

DR. XIN YU TO DEVELOP NEW CADIOVASCULAR MRI RESEARCH PROGRAM AT CASE BME

The Department of Biomedical Engineering is excited to appoint Dr. Xin Yu as Associate Professor of Biomedical Engineering at Case Western Reserve University .  Dr. Yu, a noted expert in Cardiovascular MRI, devotes her research to the integrative study of the cardiovascular system. Dr. Yu received her B.Sc. degree in Electrical Engineering at University of Science and Technology of China , her M.S. degree in Electrical Engineering at Johns Hopkins University , and her Sc.D. in Radiological Sciences at MIT .

Dr. Yu's research focuses on developing magnetic resonance imaging (MRI) and spectroscopy (MRS) techniques for phenotypic characterization of cardiovascular diseases in both humans and animal models, and applying these techniques to elucidate the structure-function and energy-function relationships in diseased hearts. She is interested in both basic science and translational clinical research that combines the state-of-the-art NMR technology with molecular biology approaches to explore the mechanisms of myocardial remodeling in diseased hearts. Currently, she is investigating the myocardial remodeling processes in genetically manipulated mouse models, muscular dystrophy and diabetes in particular.

Dr. Yu's research elucidates the molecular mechanisms responsible for altered cardiac function by integrating the investigation of the cardiovascular system at different levels, from cultured myocytes to in vivo MRI experiments. •  Upper Left: Parametric image map of myocardial fiber orientation acquired from diffusion tensor MRI •  Upper Center: 31P MR spectrum of metabolites from a perfused heart •  Upper Right: Parametric image map of myocardial torsion acquired from in vivo MRI •  Lower Left: Isolated cultured myocytes from an adult mouse heart •  Center Left: The isolated perfused (Langdorff) mouse heart for structural and energetic studies •  Lower right: Experimental settings of in vivo MR imaging experiments

Dr. Yu is also excited to participate in teaching. She will teach a lecture in EBME 410 (Medical Imaging Fundamentals) in Fall 2004, and she will teach cardiac physiology, MRI physics, and related subjects in future academic semesters. Her research and teaching interests are an ideal match for the Department of Biomedical Engineering at Case and the University Hospitals.

Dr. Yu has relocated to Cleveland with her two sons Marty (8 years old) and Matt (6 yeas old). Her husband, a urologist, is expected to join the faculty of the department of urology at University Hospital after he finishes his fellowship at the Memorial Sloann-Kettering Cancer Center in New York City next year.

Related links:
Faculty Profile
BME Imaging Research

News story contributed by Zhong Wang