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case western reserve university

Biotherapeutics

Engineering Lab

 

BIOTEL Publications

1.   Young Jik Kwon, Hong Yu, and Ching-An Peng. Enhanced retroviral transduction of 293 cells cultured on liquid-liquid interface. Biotechnology and Bioengineering 72, 331-338 (2001)

2.   Young Jik Kwon and Ching-An Peng. Impact of cell growth morphology on retroviral transduction: Effect of contact inhibition. Biotechnology Progress 17, 240-246 (2001)

3.   Young Jik Kwon and Ching-An Peng. Transduction rate constant as more reliable index quantifying efficiency of retroviral gene delivery. Biotechnology and Bioengineering 77, 668-677 (2002)

4.   Young Jik Kwon and Ching-An Peng. Engineering analysis of ex vivo retroviral transduction systems. Annals of Biomedical Engineering 30, 731-742 (2002)

5.   Young Jik Kwon and Ching-An Peng. Calcium-alginate gel bead crosslinked with gelatin as potential microcarrier for anchorage-dependent cell culture. BioTechniques 33, 212-218 (2002) (Selected as a BioSpotlight of the issue)

6.   Young Jik Kwon and Ching-An Peng. Evaluation of retroviral production systems using quantitative analysis. Biotechnology Progress 19, 528-537 (2003)

7.   Young Jik Kwon, Gene Hung, W. French Anderson, Ching-An Peng, and Hong Yu. Determination of Infectious retrovirus concentration from colony-forming assay with quantitative analysis. Journal of Virology 77, 5712-5720 (2003)

8.   Stephany M. Standley, Young Jik Kwon, Niren Murthy, Jun Kunisawa, Nilabh Shastri, and Jean M. J. Fréchet. Acid-eegradable particles for protein-based vaccines: Enhanced survival rate for tumor-challenged mice using ovalbumin model. Bioconjugate Chemistry 15, 1281-1288 (2004)

9.   Young Jik Kwon, Stephany M. Standley, Andrew P. Goodwin, Elizabeth R. Gillies, and Jean M. J. Fréchet. Directed antigen presentation using polymeric microparticulate carriers degradable at lysosomal pH for controlled immune responses. Molecular Pharmaceutics 2, 83-91 (2005)

10. Young Jik Kwon and Ching-An Peng. High-yield retroviral production using temperature modulated two-stage operation. Biotechnology and Bioengineering 90, 365-372 (2005)

11. Young Jik Kwon, Stephany M. Standley, Sara L. Goh, and Jean M. J. Fréchet. Enhanced antigen presentation and immunostimulation of dendritic cells using acid-degradable cationic nanoparticles. Journal of Controlled Release, 105, 199-212 (2005)

12. Young Jik Kwon, Edward James, Nilabh Shastri, Jean M. J. Fréchet. In vivo targeting of dendritic cells for activation of cellular immunity using vaccine carriers based on pH-responsive microparticles.  Proceedings of the National Academy of Sciences in the United States of America, 102, 18264-18268 (2005)