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BIOMEDICAL ENGINEERING
 
 

Xin Yu , Sc.D.

Associate Professor
Office: Room 519 Wickenden Building
Phone: (216)-368-3918
Fax: (216)-368-4969
Email: Xin.Yu@case.edu
Mail Address:Room 319 Wickenden Building
10900 Euclid Avenue
Cleveland, OH 44106-7207
Selected links:
• Department of Biomedical Engineering
• Curriculum Vitae (PDF Version)
• Curriculum Vitae (HTML Version)
• PubMed Citations >>

Xin Yu, Sc.D.
Curriculum Vitae

EDUCATION
• 1986 B.Sc. in Electrical Engineering
 University of Sciences and Technology of China
• 1990 M.S. in Electrical Engineering
  The Johns Hopkins University, Baltimore, MD
• 1996 Sc.D. in Radiological Sciences,
  Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA
 
POSTDOCTORAL TRAINING
• 1996-1999 Research Associate in Radiology,
 Duke University Medical Center
 
ACADEMIC APPOINTMENTS
•  1999-2001 Instructor in Medicine,
Washington University School of Medicine, St. Louis, MO
• 2001-2004 Affiliate Lecturer in Biomedical Engineering,
Washington University, St. Louis, MO
• 2001-2004 Research Assistant Professor of Medicine,
Washington University School of Medicine, St. Louis, MO
• 2004- Associate Professor of Biomedical Engineering,
Case Western Reserve University, Cleveland, OH
 
HONORS AND AWARDS
• 1989-1990 Wolman Fellowship of W.G.C. Whiting School of Engineering,
The Johns Hopkins University
• 1993-1994 Clement Vaturi Fellowship in Biomedical Engineering,
Massachusetts Institute of Technology
 
PUBLICATIONS
•  Lewandowski ED, LA Damico, LT White, X Yu. Cardiac responses to induced lactate oxidation: NMR analysis of metabolic equilibria. Am. J. Physiol. 38: H160-H168, 1995.
•  Yu X, LT White, C Doumen, LA Damico, KF LaNoue, NM Alpert, ED Lewandowski. Kinetic analysis of dynamic 13 C NMR spectra: metabolic flux, regulation, and compartmentation in hearts. Biophysical J. 69: 2090-2102, 1995.
•  Lewandowski ED, C Doumen, LT White, KF LaNoue, LA Damico, X Yu. Multiplet structure of 13C NMR signal from glutamate and direct detection of tricarboxylic acid (TCA) cycle intermediates. Magn. Reson. Med. 35: 149-154, 1996.
•  Damico LA, LT White, X Yu, ED Lewandowski. Chemical versus isotopic equilibrium and the metabolic fate of glycolytic end products in the heart. J. Mol. Cell Cardiol. 28: 989-999, 1996.
•  Yu X, LT White, NM Alpert, ED Lewandowski. Subcellular metabolite transport and carbon isotope kinetics in the intramyocardial glutamate pool. Biochemistry 35: 6963-6968, 1996.
•  Lewandowski ED, X Yu, KF LaNoue, LT White, C Doumen, JM O'Donnell. Altered metabolite exchange between subcellular compartments in intact postischemic rabbit hearts. Circ. Res. 81: 165-175 , 1997.
•  Yu X, NM Alpert, ED Lewandowski. Modeling enrichment kinetics from dynamic 13C NMR spectra: theoretical analysis and practical considerations. Am. J. Physiol. 272: C2037-C2048 , 1997.
•  O'Donnell JM, C Doumen, KF LaNoue, LT White, X Yu, NM Alpert, ED Lewandowski. Dehydrogenase regulation of metabolite oxidation and efflux from mitochondria in intact hearts. Am. J. Physiol. 274: H467-H476 , 1998.
•  Yu X, SK Song, J Chen, MJ Scott, RJ Fuhrhop, CS Hall, PJ Gaffney, JJH Ackerman, SA Wickline, GM Lanza. High resolution MRI characterization of human thrombus using a novel fibrin-targeted paramagnetic nanoparticle contrast agent. Magn. Reson. Med. 44: 867-872, 2000.
•  GM Lanza, DR Abendschein, X Yu, PM Winter, K Karukstis, MJ Scott, RW Fuhrhop, DE Scherrer, SA Wickline. Molecular imaging and targeted drug delivery with a novel, ligand-directed paramagnetic nanoparticle technology. Acad Radiol, 9:S330-1, 2002.
•  GM Lanza, X Yu, PM Winter, DR Abendschein, KK Karukstis, MJ Scott, LK Chinen, RW Fuhrhop, D Scherrer, SA Wickline. Targeted antiproliferative drug delivery to vascular smooth muscle cells with a magnetic resonance imaging nanoparticle contrast agent: implications for rational therapy of restenosis. Circulation. 106: 2842-2847, 2002.
•  PM Winter, SD Caruthers, X Yu, S-K Song, RW Fuhrhop, S Love, J Chen, B Miller, JWM Bulte, SA Wickline, GM Lanza. Relaxivity of paramagnetic nanoparticles for molecular imaging depends on chelate conformation. Magn. Reson. Med. 50:411-416, 2003.
•  J Chen, S Song, W Liu, M McLean, S Allen, J Tan, SA Wickline, X Yu. Alterations in myocardial fiber structure in post-infarct remodeled rat heart observed with diffusion tensor MRI. Am. J. Physiol. 285:H946-H954, 2003.
•  AM Morawski, PM Winter, X Yu , RW Fuhrhop, MJ Scott, F Hockett, JD Robertson, PJ Gaffney, GM Lanza, SA Wickline. Quantitative "magnetic resonance immunocytochemistry" with ligand-targeted 19 F nanoparticles. Magn. Reson. Med. 52:1255-1262, 2004.
•  W Liu, J Chen, S Ji, JS Allen, PV Bayly, SA Wickline, X Yu. HARP MRI tagging for direct quantification of Lagrangian strain in rat hearts after myocardial infarction. Magn. Reson. Med. 52:1282-1290, 2004.

 

 

This page was last modified July 29, 2008