EBME 513. Biomedical Optical Diagnostics
Course Syllabus
Lecture Topics
I. Classical optics review
Wave and ray optics; diffraction and Fourier optics; interferometry; and polarization
II. Light scattering
Elastic light scattering; elastic scattering tissue spectroscopy; laser-induced fluorescence/luminescence spectroscopy and laser Raman microscopy/spectroscopy
III. Light microscopy
Microscopy; confocal microscopy; interference microscopy; multiphoton microscopy; laser tweezers; near field optics and fluorescence methods.
IV. Modern Optics Essentials
Ray transfer matrices; Gaussian beam propagation; laser cavity mode analysis, ultrafast optics technology; optical lens design (Zemax)
V. Light-Tissue Interaction
Optical properties of tissue; radiation transport theory, diffusion approximation; Monte Carlo light propagation models
VI. Tissue Imaging
Spectroscopic imaging; polarization-based imaging; optical computed tomography; Diffuse optical tomography; holography, speckle imaging
VII. Optical Coherence Tomography
Optical coherence tomography (theory and technology); functional imaging extensions to optical coherence tomography
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