EBME 513. Biomedical Optical Diagnostics
Credit Hours: 3-0-3
Class Times: Tuesday and Thursday 1:15-2:30pm
Location: Wickenden 301
Prerequisities: PHYS 326 or equivalent
Catalog Description
Engineering design principles of optical instrumentation for medical diagnostics. Elastic and inelastic light scattering theory and biomedical applications. Confocal and multiphoton microscopy. Light propagation and optical tomographic imaging in biological tissues. Design of minimally invasive spectroscopic diagnostics.
Description and Motivation
The recent explosion of interest in minimally invasive medical diagnostics has been fueled in part by the development of novel optics and photonics techniques and instrumentation designed specifically for medical applications. A large number of optically-based imaging and sensing diagnostics are now in use in both the research laboratory and medical clinic. In addition, pursuit of state of the art research in several biomedical engineering sub-fields requires a high level of sophistication in contemporary optical technologies. In this course, students will gain exposure to the most important optical diagnostic techniques in use by researchers and clinicians. This graduate course will include sufficient reviews of classical and modern optics to allow the student to grasp fundamental aspects of light interaction with biological tissues. Students will gain experience with Monte Carlo computational methods for photon migration calculations and optical design using Zemax. In addition, a number of topics will be covered representing areas undergoing rapid development and novel applications.
The anticipated student audience for this course includes:
1) Students who anticipate further research in the expanding area of biophotonics
2) Students involved in biomedical engineering research areas that depend heavily upon modern optics technologies (e.g., biomaterials characterization, sensor development, quantitative microscopies)
3) Students from BME and other departments with interests in contemporary optics topics (i.e., scattering theory, microscopy, ultrafast optics) which are not addressed in other courses at CWRU.
Grading
Grading for the course will be based upon required assignments, projects and presentations. The assignments will also include reading published papers that demonstrate the applicability of the lecture material to relevant problems in biomedical optics.
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