EBME 426. Biomaterials and Drug Delivery
Course Syllabus
Course Materials
Review papers (50%)*
Supplementary textbooks (30%): Drug Delivery by M. Salztman, Gene Therapy and Gene Delivery Systems by D. Schaffer and W. Zhou
Research Papers (20%)*
*Selected from Science, Nature, Nat Med, Nat Biotechnol, Nat Mat, Proc Natl Acad Sci, J Control Rel, Gene Ther, Pharm Res, J Am Chem Soc, Hum Gene Ther, Cancer Gene Ther, J Virol, Biotech Bioeng, Mol Pharm, Mol Ther, Bioconj Chem, Nano Lett, etc.
Course Topics
1. Introduction to gene and drug delivery
2. Overview of genetic diseases
3. Gene delivery vehicles
4. Gene transfer processes and limitations
5. Quantitative analysis of gene delivery systems
6. Stem cell gene therapy
7. Clinical cases in gene therapy
8. Drug delivery materials
9. Targeted drug delivery
10. Drug transport & Pharmacokinetics
11. Various drug releasing mechanisms (e.g., Image-guided drug delivery)
12. Nanomedicine
13. Clinical Cases in drug delivery
Evaluation
Homework: 20%, Midterm: 20% Final: 30%, Term project (Writing a Review Paper): 15% (Paper) + 15% (presentation)
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