EBME 416. Biomaterials for Drug Delivery
Description
This course is designed to provide students with a basic understanding of the principles behind controlled release drug delivery. Through lectures, paper reviews, in class discussions and homework assignments, students will develop an in depth understanding of the various ways a drug can be administered to the body and how these approaches have overcome the problems associated with typical oral and intravenous administration. Various types of drug and gene delivery routes including transdermal, implantable, targeted and pulmonary will be discussed. The course will highlight the rational design of drug delivery devices based on the fundamental understanding in pharmacology, chemistry, biomaterials science and engineering. Integration of biomaterial structure and function will be emphasized throughout the course.
Prerequisites
EBME 306 or graduate standing
Course Objectives
1. Develop the ability to apply a rational design to drug delivery by understanding pharmacology, chemistry, biomaterials science and engineering.
2. Understand the relationship between modifying parameters such as formulation, controlled release, environmental response, and molecular targeting and their clinical outcomes in tissues or disease states.
3. Learn the ability to evaluate the strengths and weaknesses of existing therapies and propose novel designs to address these limitations.
Prerequisites
Class/laboratory Schedule
White 411 10:00-11:15 am, Tuesday and Thursday
Typical Class Size
Semesters and Years Offered
Offered fall semester every year.
Textbooks
Drug Delivery: Engineering Principles for Drug Therapy. Mark Saltzman, Oxford University Press, 2001 ISBN: 0195085892 (recommended)
See the syllabus for additional reading
Exams
There will be two exams and a final during the semester. Each will generally cover the material from that section of the semester, but will also integrate knowledge from all previous sections. Therefore all knowledge will be cumulative. |
