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BIOMEDICAL ENGINEERING

 
 

EBME 407. Neural Interfacing

Course Syllabus

Textbook
Class notes and selected fundamental journal articles

References
Neural Prostheses for Restoration of Sensory and Motor Function. Chapin, Moxon
Neural Prostheses: Fundamental Studies. Agnew, McCreary
Electrical Nerve Stimulation: Theory, Experiments and Applications. Rattay
Bioelectric Phenomena. Plonsey
The Physiology of Excitable Cells. Aidley
Ion Channels of Excitable Cells. Hille
Electrical Current Flow in Excitable Cells. Jack, Tsien, Noble
Electric Fields in the Brain. Nunez

Course Topics
1. Introduction to Applied Neural Control
2. Neural Systems: Neurons and Axons
3. Passive Properties, Cable Equation, Electrotonic properties of neural tissue
4. Volume conduction, Quasi-static formulation of the Maxwell equations, Electric fields in homogeneous volume conductors, Solution in inhomogeneous media
5. Membrane response to applied fields
6. Volume conduction
7. Principles of magnetic stimulation
8. Electrical stimulation of axons, Non-linear membrane models: HH, FH, Non-linear membrane models: CRRSS, SRBMG, Stimulation of axons: McNeal Model, Stimulation of Central Neurons: MG Model; Gen. AF, Characterizing excitation of axons, Total Driving function(s)
9. Principle of Neural Recording
10. Current Density at electrodes
11. Axonal Block: AC/DC, Tripolar, Monopolar, Bipolar
12. Electrochemistry of stimulation electrodes, Electrode interface, Electrode potential, Monophasic/Biphasic
13. Tissue Damage, Material Properties, Electrodes
14. Recruitment properties of electrodes

This page was last modified November 18, 2009