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case western reserve university

 
Danny R. Gray, PhD

Postdoctoral Fellow

DEGREE:
PhD in Cellular and Molecular Pathology, University of North Carolina       at Chapel Hill, 2005
BS in Biology, Radford University,1990

CURRENT RESEARCH: Targeted delivery of embryonic stem cell derived endothelial precursor cells to organ specific vascular beds to repair endothelium damaged by various pathologic precesses.

CONTACT: danny (dot) gray (at) case (dot) edu

Danny completed undergraduate studies in biology then gained technical experience to complement science as a communications officer in the United States Army and as a computer programmer, database designer/manager, network administrator, and technology instructor. During which time he gained a fascination with hematology through discussions with his wife, Laurie Gray, a medical technologist and research laboratory technician. Returning to biological science as a technician in 1998, Danny worked in immunology and blood coagulation before applying to graduate school and completing his doctoral research characterizing the vasculature of human prostate cancer and benign prostatic hyperplasia in a nude mouse model. Danny is a father of a sweet 4-year-old daughter, a home brewer, and a pre-beginner guitarist.

PUBLICATIONS:

Gray DR, Shapiro N, Yano K, Shih SC, Aird WC. Multi-gene transcriptional profiling of circulating blood and endothelial cells: A high throughput characterization of the host response to sepsis. (In Preparation)

Gray DR, Buckley BK, Huss WJ, Yau JM, Werdin ES, Schell MJ, Smith GJ. Androgen deprivation induces rapid vascular involution and recovery in the short-term human prostate primary xenograft model. (In Preparation)

Huss WJ, Gray DR, Tavakoli K, Marmillion ME, Durham LE, Johnson MA, Greenberg NM, Smith GJ. Origin of androgen insensitive poorly-differentiated tumors in the transgenic adenocarcinoma of mouse prostate model (TRAMP). Neoplasia. 2007;9(11):938-50.

Huss WJ, Gray DR, Greenberg NM, Mohler JL, Smith GJ. Breast cancer resistance protein-mediated efflux of androgen in putative benign and malignant prostate stem cells. Cancer Research. 2005;65(15):6640-50.

Gray DR, Huss WJ, Yau JM, Durham LE, Werdin ES, Funkhouser Jr. WK, Smith GJ. Short-term human prostate primary xenografts: an in vivo model of human prostate cancer vasculature and angiogenesis. Cancer Research. 2004;64:1712-21.

Huss WJ, Gray DR, Werdin ES, Funkhouser WK, Smith GJ. Evidence of pluripotent human prostate stem cells in a human prostate primary xenograft model. The Prostate. 2004;60(2):77-90.

PREVIOUS LABS:

William Aird Lab at Beth Israel Deaconess Medical Center/Harvard Medical School

Gary Smith Lab, previosly at UNC at Chapel Hill, now at Roswell Park Cancer Institute

Howard Reisner Lab, UNC at Chapel Hill