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Biomimetic tissue engineering; innovative biomaterials and drug delivery vehicles for functional tissue
regeneration and cancer therapy; control of stem cell differentiation; mechanotransduction and the
influence of mechanics on cell and tissue function; cell-cell interactions. |
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High resolution imaging of endogenous gene expression; definition of molecular signatures for imaging
and treatment of cancer; generating and utilizing genomic data to define informative targets; applying
non-invasive imaging to drug development; novel molecular imaging probes and paradigms. |
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Tissue Engineering, Cell/cellular transport processes in inflammation, wound healing, and cancer metastasis. |
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Neural Engineering, neural Interfacing, neural prostheses, computation neuroscience, neurophysiology
and control of epilepsy. |
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Biomaterials, instrumentation, nanoscale structure-function analysis of orthopaedic biomaterials; scanning
probe microscopy and spectroscopy of skeletal tissues. |
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Biomedical sensing and diagnostics in vitro and in vivo; electrochemical and optical techniques;
BioMEMS for cellular transport; cancer multidrug resistance at the single cell level; sliver sensor for
multianalyte patient monitoring. |
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Neural engineering; neural prostheses; neurophysiology and neural control of genitourinary function;
devices to restore genitourinary function; functional neuromuscular stimulation. |
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Restoration of movement using neuroprostheses; neuroprosthesis control system design; natural control
of human movements; biomechanics of movement; computer-based modeling; system identification. |
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Develop preventative treatment and replacement measures for bone disease and failure; Multi-scale
modeling of the interplay between mechanics and transport in biological systems: cell mechanics;
tissue engineering. |
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Development of semi-artificial viral vectors; Synthesis of polymeric gene carriers; Targeted drug delivery;
Cancer vaccine; In vivo imaging; Bioartificial liver; Stem cell bioreactors; Mathematical modeling. |
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Self-assembling biomimetic materials; vascular tissue engineering, novel biomaterials for surface modification
of cardiovascular devices and hydrogels for tissue engineering; targeted liposome drug delivery;
bacterial adhesion; cell and protein interactions with biomaterials using atomic force microscopy. |
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Molecular Imaging; MR imaging of functional and molecular biomarkers; MR high throughput screening
methods. |
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Biomedical optics, optical biomedical diagnostics, novel optical methods for high-resolution, minimally
invasive imaging, tissue characterization and analyte sensing; real-time in vivo microstructural, functional,
and molecular imaging using optical coherence tomography. |
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Mass transport, heat transport, and metabolism in cells, tissues, and organs; mathematical modeling,
simulation, nonlinear parameter estimation, and optimal experiment design applied to biomedical systems. |
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Targeted Drug Delivery; Targeted Molecular Imaging; Image-guided Therapy; Platelet Substitutes;
Novel Polymeric Biomaterials for Tissue Engineering Scaffolds. |
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Brain-computer interfaces computer control; neural prostheses & robotic devices; Invasive & noninvasive
brain signal acquisition; Adaptive decoding algorithms to retrain brain to control alternative
devices after paralysis. |
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Neuromimetic neuroprostheses; laryngeal neuroprostheses; clinical implementation of nerve electrodes;
cortical neuroprostheses; minimally invasive implantation techniques; modeling of neural stimulation
and neuroprostheses. |
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Tissue engineered epithelia; pre-vascularized polymer scaffolds for tissue engineering; directed stem
cell differentiation; novel stimuli responsive biomaterials for gene and drug delivery; systems biology
approaches to the identification of angiogenic factors. |
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Biomedical image processing; digital processing and quantitative image quality of X-ray fluoroscopy images;
interventional MRI. |
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Cardiovascular physiology; magnetic resonance imaging and spectroscopy; characterization of the
structure-function and energy-function relationships in normal and diseased hearts; small animal imaging
and spectroscopy. |
