Description
This course is designed to provide students with a basic understanding of the principles behind controlled release drug delivery. Through lectures, paper reviews, in class discussions and homework assignments, students will develop an in depth understanding of the various ways a drug can be administered to the body and how these approaches have overcome the problems associated with typical oral and intravenous administration. Various types of drug and gene delivery routes including transdermal, implantable, targeted and pulmonary will be discussed. The course will highlight the rational design of drug delivery devices based on the fundamental understanding in pharmacology, chemistry, biomaterials science and engineering. Integration of biomaterial structure and function will be emphasized throughout the course.

Prerequisites
One year of introductory biomaterials class (e.g. EBME 306). Required:  PHRM 309/409.

Class/laboratory Schedule
Bingham 204  4:15-4:30pm, Tuesday and Thursday

Typical Class Size
50

Semesters and Years Offered
Offered spring semester every year.

Textbooks
Drug Delivery:  Engineering Principles for Drug Therapy. Mark Saltzman, Oxford University Press, 2001 ISBN: 0195085892 (recommended)
See the syllabus for more recommended reading

Exams
There will be three exams and a final during the semester.  Each will generally cover the material from that section of the semester, but will also integrate knowledge from all previous sections.  Therefore all knowledge will be cumulative.

Computer Usage
The students need to know how to use Matlab and will use it extensively in this course.