Biomedical engineering fields of activity. Research, development, and design for biomedical problems, diagnosis of disease, and therapeutic applications. test

Cell physiology. Electrophysiology of nerve and muscle. Motor system. Central nervous system. Sensory systems. Autonomic nervous system.

Biological control systems. Cardiovascular, renal, respiratory, gastro-intestinal, and immune systems.

Structure of proteins, nucleic acids, connective tissue and bone from molecular to microscopic levels. Principles and applications of instruments for imaging, identification, and measurement of biological materials.

Applications of biomaterials in different tissue and organ systems. Relationship between physical and chemical structure of materials and biological system response. Choosing, fabricating and modifying materials for specific biomedical applications.

Neuromuscular prosthetic systems. Functional electrical stimulation. Restoration of movement of paralyzed arms and legs. Design of implantable systems. Regulatory and ethical considerations.

Quantitative analysis of biomedical signals and physiological systems. Fourier and Laplace transforms. Frequency response of systems and circuits. A/D conversion, sampling, and discrete-time signal processing. Filter design. Laboratory and computational experiences with biomedical applications.

Mathematical modeling and computer simulation with biomedical applications. Neuromuscular control of skeletal movement. Mass transport processes in blood dialysis. Analysis of cardiac electrial activity. Biomechanics of bone.

Physical, chemical and biological principles for biomedical measurements. Modular blocks and system integration. Sensors for displacement, force, pressure, flow, temperature, biopotentials, chemical composition of body fluids and biomaterial characterization. Patient safety.

Experiments for measurement, assist, replacement, or control of various biomedical systems.

Continuation of EBME 313.

The teaching objective is to provide students with a basic understanding of the principles of design and engineering of well-defined molecular structures and architectures intended for applications in controlled release and organ-targeted drug delivery. The course will discuss the therapeutic basis of drug delivery based on drug pharmacodynamics and clinical pharmacokinetics. Biomaterials with specialized structural and interfacial properties will be introduced to achieve drug targeting and controlled release.

Prerequisites

One year of introductory biomaterials class (e.g. EBME 306). Required:  PHRM 309/409.

Ion channels are the molecular basis of membrane excitability in all cell types, including neural, heart, and muscle cells. This course presents the structure and the mechanism of function of ion channels at the molecular level. It introduces the basic principles and methods in the ion channel study including the ionic basis of membrane excitability, thermodynamic and kinetic analysis of channel function, voltage clamp and patch clamp techniques, and molecular and structural biology approaches. The course will cover structure of various potassium, calcium, sodium, and chloride channels and their physiological function in neural, cardiac, and musclecells. Exemplary channels that have been best studied willbe discussed to illustrate the current understanding of themolecular mechanisms of channel gating and permeation.

Experiments for measurement, assist, replacement, or control of various biomedical systems.

Continuation of EBME 318.

Physical principles of medical imaging. Imaging devices for x-ray, ultrasound, magnetic resonance, etc. Image quality descriptions. Patient risk.

Computer hardware and software systems for use in biomedical engineering devices/instruments and laboratories. Topics include computer architecture, digital and analog interfaces, sampling requirements, and real-time programming for control and data collection. Applications in biology and medicine are emphasized, with hands-on experience obtained by laboratory exercises using the LabVIEW programming language.

This course will present the primary components, design principles, and engineering concepts central to the field of tissue engineering.

This course will provide research and development in the laboratory of a mentoring faculty member. Varied R&D experiences will include activities in biomedical instrumentation, tissue engineering, imaging, drug delivery, and neural engineering. Each Student must identify a faculty mentor, and together they will create description of the training experience prior to the first class.

This course will provide research and development training in the laboratory of a mentoring faculty member. Varied R&D experiences will include activities in biomedical instrumentation, tissue engineering, imaging, drug delivery, and neural engineering. Each student must identify a faculty mentor,and together will create a description of the training experience prior to the first class.

The objective of this course is to equip the students with a "molecular toolbox"--a set of quantitative skills that permit rational designs for engineering tissues starting at themolecular level. The course will build on the physical and chemical principles in equilibrium, kinetics, and mass transport. Specific examples in bioengineering systems will be used throughout the course to illustrate the importance of understanding and application of these principles to tissue engineering of skin and cartilage.

Please see EBME 309

The design process required to produce biomedical devices, research equipment, and clinical tools is developed.

Design of a clinically useful product with potential commercial value.

Senior project lab.

Second semester continuation of EBME398, senior project lab.