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Junmin Zhu, Ph.D. Research Assistant Professor
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Selected links:
• Center for Cardiovascular Biomaterials
• Case Comprehensive Cancer Center
Research Summary
Major interests include: (1) biomimetic engineering of nanomaterials, including lipidic vesicles, core-shell nanoparticles, nanogels and nanofibers; (2) engineering extracellular matrix (ECM)-mimetic hydrogels and nanostructured scaffolds for bioengineering vascular grafts and networks; (3) engineering of multifunctional nanosystems for targeting tumor angiogenesis. The underlying theme is to combines expertise in nanoscale design and engineering of biomaterials with molecular level control of cell/materials interactions in order to translate key advances in materials science and nanotechnology into better solutions for vascular tissue regeneration and cancer-related diagnosis and therapy.
Recent Publications
Zhu J. Bioactive modification of poly(ethylene glycol) hydrogels for tissue engineering. Biomaterials 2010, 20, 31. DOI: 10.1016/j.biomaterials.2010.02.044.
Beamish JA, Zhu J, Kottke-Marchant K, Marchant RE. The effects of monoacrylated poly(ethylene glycol) on the properties of poly(ethylene glycol) diacrylate hydrogels used for tissue engineering. Journal of Biomedical Materials Research 2010, 92A, 441-450.
Zhu J, Tang C, Kottke-Marchant K, Marchant RE. Design and synthesis of biomimetic hydrogel scaffolds with controlled organization of cyclic RGD peptides. Bioconjugate Chemistry 2009, 20, 333-339.
Zhu J, Marchant RE. Solid-phase synthesis of tailed cyclic RGD peptides using glutamic acid: unexpected glutarimide formation. Journal of Peptide Science 2008, 14, 690-696.
Zhu J, Xue J, Guo Z, Zhang L, Marchant RE. Biomimetic glycoliposomes as nanocarriers for targeting P-selectin on activated platelets. Bioconjugate Chemistry 2007, 18, 1366-1369.
Buxton AN, Zhu J, Marchant RE, West JL, Yoo JU, Johnstone B. Design and characterization of poly(ethylene glycol) photopolymerizable semi-interpenetrating networks for chondrogenesis of human mesenchymal stem cells. Tissue Engineering 2007, 13, 2549-2560.